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Product Information:

PHA-767491 hydrochloride

PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.

Cat. No.: EX-A792    Purity: >98%
Chemical
Chemical structure of PHA-767491 hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg550In-stock
1g750In-stock
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CAS No.845714-00-3
Purity>98%
FormulaC12H12ClN3O
Mol Weight249.696
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Montagnoli A, et al. Nat Chem Biol, 2008, 4(6), 357-365.

[2]. Yecies D, et al. Blood, 2010, 115(16), 3304-3313.

[3]. Erbayraktar Z, et al. Cell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness. Cancer Cell Int. 2016 Nov 18;16:88.
CoACoA of PHA-767491 hydrochloride
Smiles:Cl.O=C1NCCC2=C1C=C(N2)C1=CC=NC=C1

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